Tis­sue Ban­king

It is in­dis­pens­a­ble to store hu­man tis­su­es of LCH pa­ti­ents in tis­sue banks in or­der to gain a bet­ter un­der­stan­ding of the di­sea­se. The most im­portant ques­ti­ons that must be ad­dres­sed are:

· Is the­re a ge­ne­tic ba­sis for the di­sea­se ?
· Can we find so­me bio­lo­gi­cal mar­kers to mo­ni­tor the di­sea­se and to ad­opt the the­ra­py?
· Are the­re any mo­le­cu­lar al­te­ra­ti­ons that could ser­ve as tar­gets for new the­ra­pies?

Who is Or­ga­nising Ban­king?
Each tis­sue bank must be pro­fes­sio­nal­ly or­ga­ni­zed:

· Iden­ti­fi­ca­ti­on of the ori­gin of each samp­le
· Safe con­di­ti­ons of sto­ra­ge
· Writ­ten plan for the pro­tec­tion of pri­va­te in­for­ma­ti­on, in­clu­ding the pre­ven­ti­on of un­aut­ho­ri­zed ac­cess to di­gi­tal da­ta

The­re should be a pos­si­bi­li­ty to de­li­ver tis­su­es on de­mand for a pre­ci­se re­se­arch. The con­di­ti­ons of any de­li­very must be cle­ar­ly re­gu­la­ted.

Re­gu­la­ti­ons of Tis­sue Ban­king
Se­veral le­vels of re­gu­la­ti­on exist for tis­sue banks:

· Ethi­cal re­gu­la­ti­ons
· Tech­ni­cal re­gu­la­ti­ons
· Scientific re­gu­la­ti­ons

They may be de­fi­ned in in­ter­na­tio­nal re­gu­la­ti­ons, in na­tio­nal re­gu­la­ti­ons, and in re­gu­la­ti­ons ap­plied in the re­spec­tive in­sti­tu­ti­on. In ca­se of ex­ter­nal col­la­bo­ra­tors, both the col­lec­tor and the col­la­bo­ra­tor must com­ply with all their in­ter­na­tio­nal, na­tio­nal, and in­sti­tu­tio­nal re­gu­la­ti­ons.

Consent from Pa­ti­ents and Fa­mi­lies
Tis­sue ban­king is not pos­si­ble wi­t­hout the pa­ti­ent’s in­for­med consent. For child­ren, the consent must be ob­tai­ned from a per­son with pa­ren­tal re­spon­si­bi­li­ty. Ne­vert­he­less, young pa­ti­ents should be in­vol­ved as much as pos­si­ble in any de­ci­si­on con­cerning their ca­re. For other le­gal­ly in­com­pe­tent pa­ti­ents, consent is to be ob­tai­ned from a le­gal guar­di­an. No per­son can gi­ve consent on be­half of a pa­ti­ent who has re­ached the age of 18 and is le­gal­ly com­pe­tent.

The in­for­med consent must con­tain at least the fol­lo­wing in­for­ma­ti­on:
· How tis­su­es will be col­lec­ted and stored
· How me­di­cal in­for­ma­ti­on about the pa­ti­ent will be stored
· How tis­su­es will be used in re­se­arch
· What in­for­ma­ti­on will be pro­vi­ded to re­se­ar­chers
· How the pa­ti­ent can con­ta­ct the tis­sue bank ad­mi­nis­tra­tor in ca­se he wants to wi­th­draw or mo­di­fy his consent for the use in fu­ture re­se­arch


Our thanks to all of our Histio Partners for their input to these pages.

Please use the form below to contact Histio UK

Your Name (required)

Your Email (required)


Your Message

Please insert the code in the box below captcha